irisolidone Property

Melting point:

190-191 °C

Boiling point:

565.5±50.0 °C(Predicted)

Density 

1.402±0.06 g/cm3(Predicted)

storage temp. 

4°C, protect from light

solubility 

Chloroform (Slightly), DMSO (Slightly)

form 

Solid

pka

6.48±0.20(Predicted)

color 

Off-White to Pale Yellow

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

irisolidone Chemical Properties,Usage,Production

Description

Irisolidone is a hydrolyzed product of kudzurin. Studies have shown that it can significantly dilate coronary arteries, cerebral arteries and peripheral blood vessels and microvessels, and can reduce vascular resistance, cholesterol and blood viscosity.

Chemical Properties

Light yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from kudzu.

Uses

Irisolidone has anti-inflammatory, antioxidant, antibacterial, anti-tumor, estrogen-like effects, and protects liver damage caused by alcoholism.

Definition

ChEBI: Irisolidone is a member of 4'-methoxyisoflavones.

Biological Activity

Irisolidone is the main isoflavone in pueraria. Irisolidone has strong hepatoprotective activity. It has a highly effective blocking effect on the anion channel VRAC.

in vitro